Christian D. Yáñez-Vélez, Department of Neurology, Hospital Juárez de México, Mexico City, Mexico E. Isay Martinez-Acosta, Department of Genetics, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México Gabriel Mendoza-Cruz, Department of Internal Medicine, Hospital Juarez de Mexico. Mexico City, Mexico


Mitochondrial diseases are not common in clinical practice, some of them are treated as myopathies or just only muscular complications of common disease (diabetes and chronic renal disease). MELAS syndrome (acronym of mitochondrial myopathy, encephalopathy, lactic acidosis, and “stroke-like” episodes) is one of them. We introduce a patient 46 years old, previously with diabetes and hypoacusis who progress to severe acidemia and heart arrest with intensive care unit management, suspecting MELAS syndrome treatment began with improving in few days and discharged with minimal complications. In this case, its clinical features and computed tomography findings lead us to suspect his diagnosis.



Keywords: MELAS. Mitochondrial encephalopathy. Hypoacusis. Myopathy. Stroke-like. Lactic acidosis.